Xolair for Food Allergies

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At Latitude, we offer Xolair (omalizumab) in conjunction with OIT for our patients who require additional protection. Xolair is an anti-IgE monoclonal antibody by Genentech and Novartis that works by inhibiting the allergic reaction process. Our clinical team can determine whether you or your child may be a good candidate for Xolair.

What is Xolair?

Xolair is an anti-IgE monoclonal antibody by Genentech and Novartis that works by inhibiting the allergic reaction process. On February 16, 2024, it was approved by the FDA for the reduction of food allergic reactions, including anaphylaxis, in people with food allergies.  

Is Xolair Approved for Food Allergies?

Yes. In February 2024, the FDA approved Xolair as the first and only medicine to reduce allergic reactions for people with one or more food allergy.

How Does Xolair Work?

Xolair is an anti-IgE monoclonal antibody that works by inhibiting the allergic reaction process. At Latitude, we offer Xolair in conjunction with OIT to increase safety for some patients. 

For more background on oral immunotherapy with anti-IgE Xolair (omalizumab), we recommend the following published studies and meta-analysis:

 

Is Xolair Covered by Insurance?

With the recent FDA approval of Xolair, it is likely to be covered by insurance. Previously, Xolair had been granted Breakthrough Therapy Designation for the prevention of severe allergic reactions to food allergy by the FDA, but this was considered an off-label usage and often not covered by insurance. If our allergist prescribes this medication for you, we can work with you and your insurance plan to help understand if there will be any out-of-pocket costs before proceeding.

 

What is Oral Immunotherapy (OIT) and How Does Xolair Work with it?

Oral Immunotherapy is a food allergy treatment that can desensitize patients to their allergens. By offering the patients small, regular, and gradually increasing amounts of the allergen, it can help build up the body’s tolerance to those foods. The goal of OIT is to protect against severe reaction to accidental exposures and increasing quality of life. Over time, OIT retrains the immune system to decrease adverse reactions to the specific allergen.

At Latitude, we offer Xolair in conjunction with OIT to increase safety for some patients.

 

Please see our FAQs for more questions on OIT and Xolair or call us with any questions you may have about oral immunotherapy.

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